Director of Operational Excellence (AI Transformation)

Use Your Power for Purpose

Our breakthroughs would not make it to the hands of patients without our dedicated and agile pharmaceutical manufacturing team. We rely on members who understand the importance and impact of their role in Pfizer's mission. Patients need colleagues like you who take pride in their work and continuously strive to improve outcomes. Your efforts ensure that patients and physicians have the medicines they need when they need them. The significance of your role cannot be overstated, as you help bridge the gap between innovation and patient care. By being part of this team, you contribute to making life-saving treatments accessible, embodying the essence of our mission to improve global health.

What You Will Achieve

In this role, you will:

• Lead the design and deployment of AI agents and workflow automations (e.g., Microsoft Copilot Studio, Power Automate) across S&OE and External Supply, embedding them in enterprise data systems to drive measurable Continuous Improvement and decision-making outcomes (deep technical / AI engineering background is not required).

• Provide Business facing OE Support to ES Clusters and/or Pfizer Center One (PC1) where required

• Lead/Support/Coach OE solutions in the ES Clusters and/or Pfizer Center One (PC1) e.g. Continuous Improvement Loop, IMEx Deployment, Innovation, Agile Transformation, Complex Investigations in alignment with the ES/OE Strategies

• Lead and/or coach Lean/Six Sigma projects for ES Clusters/PC1/CMO and support functions to diagnose and improve processes. This may also be on a regional basis

• Build OE & Innovation capabilities at the ES Clusters, PC1 and selected CMOs

• Coach the ES Clusters/PC1 on embedding a CI Culture

• Lead a Global OE program across External Supply in alignment with the ES/OE Strategies

• Lead/support ES Strategies and T5 Initiatives

• Lead/support ES IMEx

• Be an active member of the ES S&OE team in devising the OE and ES Strategies

• Passionate and competent in using AI for Continuous Improvement

Here Is What You Need (Minimum Requirements)

• BA/BS in associated discipline is required (i.e., Engineering, Industrial Engineering, Operations Management or Science) with at least 10 years of manufacturing and/or supply experience or MBA/MS with at least 9 years of experience

• 5+ years hands-on analytics/six sigma/continuous improvement experience

• Demonstrated proficiency applying personal productivity AI tools (e.g., Microsoft Copilot, Copilot Studio agents, Power Automate) to solve business or operational problems, with evidence of measurable outcomes (formal AI certification a plus; deep technical / AI engineering background is not required).

• Lean Six Sigma Black Belt trained and certified minimum

• Incumbent must be fluent both written and verbally in English.

Bonus Points If You Have (Preferred Requirements)

• AI certification(s)

• Track record of designing, building and deploying AI agents and workflow automations (e.g., Microsoft Copilot Studio, Power Automate) in an enterprise environment, with demonstrable business impact

• Proven ability to integrate Microsoft 365, Power Platform or similar tools with enterprise data sources (e.g., SharePoint, Power BI, MES, LIMS, ERP) to surface insights and trigger actions across systems

• Active engagement with emerging AI capabilities, with the judgement to evaluate and apply them responsibly at scale

• Master’s degree coupled with relevant pharmaceutical experience.

• Certified Innovation Coach

• Method 1 Train the trainer

• 5+ years coaching and certifying successful six sigma green belts and black belts  

• Proven skills in managing large scale initiatives

• Demonstrated coaching skills

• Comprehensive knowledge of a broad range of operational excellence methodologies / programs

• Ability to define, evaluate and recommend improvement opportunities across the E2E to achieve and sustain improvements

• Strong business acumen with manufacturing and supply chain experiences preferred

• Demonstrated ability to influence stakeholders at all levels of the organization and a proven track record in change management

• Strong communication and interpersonal skills to guide and / or lead diverse teams,

• Strong analytical and problem solving

• Adaptable to work priorities in response to complex and rapidly changing environment

• Ability to navigate ES organization and operate in a multicultural environment

• Develop and execute strategies with minimal guidance

  

Other Job Details:

• Last day to Apply: July 13th, 2026

• Work Location Assignment: Hybrid


The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.




Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.






To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


Manufacturing